Casts

• 

  Tom Cruise

  Frank T.J. Mackey

• 

  Philip Baker Hall

  Jimmy Gator

• 

  Philip Seymour Hoffman

  Phil Parma

• 

  Julianne Moore

  Linda Partridge

• 

  William H. Macy

  Quiz Kid Donnie Smith

• 

  John C. Reilly

  Officer Jim Kurring

• 

  Melora Walters

  Claudia Wilson Gator

• 

  Jeremy Blackman

  Stanley Spector

• 

  Jason Robards

  Earl Partridge

• 

  Melinda Dillon

  Rose Gator

• 

  Michael Bowen

  Rick Spector

• 

  April Grace

  Gwenovier

• 

  Ricky Jay

  Burt Ramsey / Narrator

• Emmanuel Johnson

  Dixon

• 

  Pat Healy

  Sir Edmund William Godfrey / Young Pharmacy Kid

• Genevieve Zweig

  Mrs. Godfrey

• Mark Flanagan

  Joseph Green

• 

  Neil Flynn

  Stanley Berry

• 

  Rod McLachlan

  Daniel Hill

• 

  Allan Graf

  Firefighter

• 

  Patton Oswalt

  Delmer Darion

• Raymond 'Big Guy' Gonzales

  Reno Security Guard

• 

  Brad Hunt

  Craig Hansen

• 

  Jim Meskimen

  Forensic Scientist

• 

  Chris O'Hara

  Sydney Barringer

• 

  Clement Blake

  Arthur Barringer

• Frank Elmore

  1958 Detective

• John Kraft Seitz

  1958 Policeman

• Cory Buck

  Young Boy

• Tim Soronen

  Infomercial Guy

• 

  Jim Ortlieb

  Middle-Aged Guy

• 

  Thomas Jane

  Young Jimmy Gator

• Holly Houston

  Jimmy's Showgirl

• Benjamin Niedens

  Little Donnie Smith

• 

  Veronica Hart

  Dentist Nurse #1

• Missy Spell Tanner

  Dentist Nurse #2

• 

  James Kiriyama-Lem

  Dr. Lee

• 

  Jake Cross

  Pedestrian #1

• Charlie Scott Jr.

  Pedestrian #2

• Juan Medrano

  Nurse Juan

• 

  John Pritchett

  Police Captain

• 

  Cleo King

  Marcie

• 

  Don McManus

  Dr. Landon

• 

  Michael Shamus Wiles

  Captain Muffy

• Jason Andrews

  Doc

• 

  John S. Davies

  Cameraman

• 

  Kevin Breznahan

  Geoff, Seminar Guy

• 

  Miguel Pérez

  Avi Solomon

• 

  Alfred Molina

  Solomon Solomon

• David Masuda

  Coroner Man

• 

  Neil Pepe

  Officer #1

• 

  Lionel Mark Smith

  Detective

• 

  Annette Helde

  Coroner Woman

• Lynne Lerner

  Librarian

• 

  Felicity Huffman

  Cynthia

• 

  Scott Burkett

  WDKK Page #1

• Bob Brewer

  Richard's Dad

• Julie Brewer

  Richard's Mom

• Nancy Marston

  Julia's Mom

• Maurey Marston

  Julia's Dad

• Jamala Gaither

  WDKK P.A.

• 

  Danny Wells

  Dick Jennings

• Amy Brown

  WDKK Page #2

• 

  Eileen Ryan

  Mary

• 

  Meagen Fay

  Dr. Diane

• Patricia Forte

  Mim

• 

  Luis Guzmán

  Luis

• Patrick Warren

  Todd Geronimo

• 

  Orlando Jones

  Worm

• Virginia Pereira

  Pink Dot Girl (voice)

• Craig Kvinsland

  Brad the Bartender

• Patricia Scanlon

  Cocktail Waitress

• 

  Henry Gibson

  Thurston Howell

• 

  Natalie Elizabeth Marston

  Julia

• Bobby Brewer

  Richard

• 

  Clark Gregg

  WDKK Floor Director

• Art Frankel

  Old Pharmacist

• 

  Matt Gerald

  Officer #2

• Guillermo Melgarejo

  Pink Dot Guy

• 

  Paul F. Tompkins

  Chad (Seduce & Destroy) (voice)

• 

  Mary Lynn Rajskub

  Janet (Frank's Assistant) (voice)

• 

  Jim Beaver

  Smiling Peanut Patron #1

• 

  Ezra Buzzington

  Smiling Peanut Patron #2

• Denise Woolfork

  Smiling Peanut Patron #3

• 

  Michael Murphy

  Alan Kligman, Esq.

• 

  Robert Downey Sr.

  WDKK Show Director

• 

  William Mapother

  WDKK Show Director's Assistant

• Larry Ballard

  WDKK Medic

• Brett Higgins

  Mackey Disciple Twin #1

• Brian Higgins

  Mackey Disciple Twin #2

• Michael Lee Phillips Jr.

  Mackey Disciple in Middle

• 

  Lillian Adams

  Donnie's Old Neighbor

• Steven Bush

  Paramedic #1

• 

  Mike Massa

  Paramedic #2

• 

  Dale Gibson

  Paramedic #3

• 

  Scott Alan Smith

  E.R. Doctor

• 

  Paul Thomas Anderson

  Man Confiscating Sign (uncredited)

• 

  Miriam Margolyes

  Faye Barringer (uncredited)

• Bruno Angelico

  Fireman #2 (uncredited)

• 

  Robert Bella

  Detective #2 (uncredited)

• 

  Greg Bronson

  Waiter (uncredited)

• Douglas Busby

  Extra (uncredited)

• Marc Davies

  Seminar Attendee #1 (uncredited)

• Bruce Gregory

  Randy (uncredited)

• 

  Phil Hawn

  Bob (uncredited)

• 

  Spencer Kayden

  Seminar Patron (uncredited)

• Brian Kehew

  Seminar Patron (uncredited)

• Michael Laren

  Officer Tom 1958 (uncredited)

• 

  Aimee Mann

  Hot Date Infomercial (uncredited)

• 

  Tom Ohmer

  Detective (uncredited)

• Colleen Pelletier

  Gameshow Audience Member (uncredited)

• Herb Santos Jr.

  21 Dealer (uncredited)

• Tom Tangen

  Drunken Dart Player (uncredited)